This is a framework for undoing the effects of the aging process. By fighting elements in each category it is hoped that the effects of aging can be undone in the same way that cars are maintained through a combination of techniques which undo the effects of normal wear and tear on the fluids and parts, etc.
De Grey defines aging as "the set of accumulated side effects from metabolism that eventually kills us", and, more specifically, as follows: "a collection of cumulative changes to the molecular and cellular structure of an adult organism, which result in essential metabolic processes, but which also, once they progress far enough, increasingly disrupt metabolism, resulting in pathology and death." He adds: "geriatrics is the attempt to stop damage from causing pathology; traditional gerontology is the attempt to stop metabolism from causing damage; and the SENS (engineering) approach is to eliminate the damage periodically, so keeping its abundance below the level that causes any pathology."
LINK: https://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence